Publications

Preclinical evaluation of ixazomib for high-risk pediatric brain tumors

Janko E, Walker FM, Slade M, Danis E, Bompada P, Martin Sobral L, Chapman J, Kaur I, Bal S, Link G, McQuillan N, Mulcahy Levy JM, Green AL, Dahl NA

bioRxiv·2026 Sep 11·DOI 10.64898/2026.09.11.750478

Preprint — not peer reviewed

H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs

Krug B, Hu B, Deshmukh S, Chen X, Gretarsson K, Kabir Z, Chen H, Andrade A, Jabbour E, Harutyunyan A, Lee J, Hulswit M, Faury D, Russo C, Johnston M, Baguette A, Dahl NA, Weil A, Ellezam B, Dali R, Blanchette M, Wilson K, Garcia B, Gallo M, Taylor M, Kleinman C, Majewski J, Lu C, Xu X, Jabado N

Nature Genetics·2026 Jun;58(6):1368–1382·PubMed 42151415

Transcriptional regulation of protein synthesis by mediator kinase represents a therapeutic vulnerability in MYC-driven medulloblastoma

Wang D, Ritz C, Luo Y, Suresh A, Pierce A, Veo B, Brunt B, Dahl N, Serkova N, Venkataraman S, Danis E, Kus K, Mazan M, Rzymski T, Vibhakar R

Nature Communications·2025 Dec 16;16(1):11152·PubMed 41402279

Single-cell multi-omics identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastoma

Veo B, Wang D, DeSisto J, Pierce A, Brunt B, Bompada PC, Donson A, Goodspeed A, Smart K, Foreman N, Dahl NA, Vibhakar R

Nature Communications·2025 Nov 25;16(1):10470·PubMed 41290646

Differential phagocytosis induces diverse macrophage activation states in malignant gliomas

Lakshmanachetty S, Riemondy K, Sanford B, Donson A, Chen V, Balakrishnan I, Prince EW, Hankinson T, Dahl N, Vibhakar R, Foreman N, Venkataraman S, Mitra S

Journal for ImmunoTherapy of Cancer·2025 Sep 5;13(9):e012211·PubMed 40166298

Development of an anti-CD99 antibody enables targeting of diffuse midline glioma

Balakrishnan I, Madhavan K, Pierce A, Michlin J, Brunt B, Lakshmanachetty S, Wang D, DeSisto J, Nuss ZJ, Davidson N, Walker F, Suresh A, Donson A, Sanford B, Jones KL, Danis EP, Mitra S, Green AL, Dahl N, Vibhakar R, Venkataraman S

Cancer Research·2025 Aug 15;85(16):3089–3110·PubMed 40424183

Detection of gene fusions and rearrangements in formalin-fixed, paraffin-embedded solid tumor specimens using high-throughput chromosome conformation capture

Galbraith K, Wu J, Sikkink K, Mohamed H, Reid D, Perez-Arreola M, Belton JM, Nomikou S, Melnyk S, Yang Y, Liechty BL, Jour G, Tsirigos A, Hermel DJ, Beck A, Sigal D, Dahl NA, Vibhakar R, Schmitt A, Snuderl M

The Journal of Molecular Diagnostics·2025 May;27(5):346–359·PubMed 40023492

SIRT2 is a regulator of the differentiation block driven by SMARCB1 loss in ATRT

Alimova I, Wang D, DeSisto J, Danis E, Lakshmanachetty S, Prince E, Murdock G, Pierce A, Donson A, Balakrishnan I, Serkova N, Lin H, Foreman N, Dahl NA, Venkataraman S, Vibhakar R

Molecular Cancer Research·2025 Feb 17·PubMed 39960392

IDH-mutant astrocytoma arising from a demyelinating plaque in a child with X-linked adrenoleukodystrophy

Kalter JA, Yang RA, Toland A, Milla S, Lund TC, Hankinson T, Dahl NA

Journal of Neuropathology & Experimental Neurology·2024 Mar 20;83(4):289–292·PubMed 38456320

Thromboembolic toxicity observed with concurrent trametinib and lenalidomide therapy

Chan P, Sabus A, Hemenway M, Chatfield K, White C, Mirsky D, Foreman NK, Dahl NA

Pediatric Blood & Cancer·2023 Mar;70(3):e30190·PubMed 36602034

PDGFB:APOBEC3C fusion in congenital diffuse high-grade glioma of the brainstem

Norris G, Donson AM, Milgrom SA, Gaskell A, Willard N, Foreman NK, Gilani A, Dahl NA

Journal of Neuropathology & Experimental Neurology·2023 Jan 20;82(2):183–186·PubMed 36440550

Peri-transplant radiation therapy for young children treated with high-dose chemotherapy for primary brain tumors

Milgrom SA, Koo J, Foreman N, Liu AK, Campbell K, Dorris K, Green AL, Dahl NA, Donson AM, Vibhakar R, Mulcahy Levy JM

Advances in Radiation Oncology·2022 Jul;7(4)·PubMed 35814855

Venetoclax cooperates with ionizing radiation to attenuate diffuse midline glioma tumor growth

Madhavan K, Balakrishnan I, Chetty SL, Pierce A, Sanford B, Fosmire S, Elajaili H, Walker F, Wang D, Nozik-Grayck E, Mitra S, Dahl NA, Vibhakar R, Venkataraman S

Clinical Cancer Research·2022 Jun 1;28(11):2409–2424·PubMed 35344040

Converging evidence for inhibition of transcriptional control in high-grade gliomas

Dahl NA, Vibhakar R

Neuro-Oncology·2021 Aug 2;23(8):1225–1227·PubMed 33984150

Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in Myc-driven medulloblastoma

Veo B, Danis E, Pierce A, Wang D, Fosmire S, Sullivan K, Joshi M, Khanal S, Dahl NA, Karam S, Serkova N, Venkataraman S, Vibhakar R

Cell Reports·2021 Apr 27;35(4):109013·PubMed 33910002

NTRK fusions can co-occur with H3K27M mutations and may define druggable subclones within diffuse midline gliomas

Dahl NA, Donson AM, Sanford B, Wang D, Walker FM, Gilani A, Foreman NK, Tinkle CL, Baker SJ, Hoffman LM, Venkataraman SV, Vibhakar R

Journal of Neuropathology & Experimental Neurology·2021;80(4):345–353·PubMed 33749791

Senescence induced by BMI1 inhibition is a therapeutic vulnerability in H3K27M-mutant DIPG

Balakrishnan I, Danis E, Katagi H, Madhavan K, Pierce A, Wang D, Sanford B, Birks DK, Davidson N, Metselaar DS, Dahl NA, Lemma R, Donson A, Vijmasi T, Sola I, Fosmire S, Alimova I, Gilani A, Serkova NJ, Hashizume R, Huellman E, Hawkins C, Carcaboso AM, Gupta N, Monje M, Jones K, Foreman N, Green A, Vibhakar R, Venkataraman S

Cell Reports·2020 Oct 20;33(3):108286·PubMed 33086074

Sacramentality in palliation

Dahl NA

Journal of Clinical Oncology·2020 Aug 10;38(23):2695–2696·PubMed 32463738

Preclinical and clinical investigation of intratumoral chemotherapy pharmacokinetics in DIPG

Green A, Flannery PC, Hankinson TC, O'Neill B, Amani V, DeSisto J, Knox A, Lemma R, Hoffman L, Mulcahy Levy J, Raybin J, Hemenway M, Gilani A, Koschmann C, Dahl NA, Handler M, Pierce A, Venkataraman S, Foreman N, Vibhakar R, Wempe M, Dorris K

Neuro-Oncology Advances·2020;2(1)·PubMed 32642682